The GLEOCEPT S -180 is administered for preventing rejection of transplanted organ in recipient’s body

Organ transplantation is already saving the lives of many people, globally during each and every year. However, the body’s immune system is acting as a significant barrier to the successful transplantation of the organ. Sometimes, the immune system of the body rejects the new organ considering it as a foreign agent. Due to this reason, the immune system is triggered as a response towards the destruction of the transplanted organ. In order to achieve the long-term success of organ transplantation, the immune system is manipulated for the reduction of the risk of organ(transplanted) rejection. The immunosuppressive drugs are administered as a way for preventing as well as treating the rejection of the transplant. This is done by suppressing the overall responsiveness of the immune system. One medication in this regard is GLEOCEPT S -180 which is indicated for managing the condition of patients who have undergone organ transplant. Being the immunosuppressant, the drug is actually working by decreasing the overall strength of the immune system of the body against transplanted organ.

Description about GLEOCEPT S -180

The GLEOCEPT S -180 is actually administered for preventing the rejection of the transplanted organ. Such type of organ rejection is taking place when the immune system of the recipient patient recognizes the transplanted organ as being a foreign agent, thereby attacking it. So it is vital to treat it promptly, otherwise, this can lead to permanent damage. The main actionable agent present in the drug is Mycophenolate sodium 180mg, and this can be indicated by the doctor in combination with the immuno- suppressive as well as the anti-inflammatory compounds. It is demonstrating the inhibitory effect on the T as well as B lymphocytes, leading to the separation of the production of antibodies. Such an effect also carries out the separation of the immune system, so that the transplanted graft rejection does not take place.

Uses of GLEOCEPT S -180

The most important utilization of the  GLEOCEPT S -180, with the main constituent Mycophenolate sodium 180mg is in the remediation for the rejection of the transplanted organ by the body’s immune system. At the same time, it also has its applicability in managing the condition of autoimmune disorder.

Some of the autoimmune diseases for which it is administered include:

• Rheumatoid arthritis
• Crohn′s disorder
• Ulcerative colitis(UC)

How GLEOCEPT S -180 is working?

The Gleocept S -180 comprises of the Mycophenolate sodium, MPS. This is the pro-drug form of the MPA(mycophenolic acid). Upon the absorption of the chemical compound MPS by the body, it is getting converted into MPA(mycophenolic acid). So the mechanism of the drug action involves the inhibition of the enzyme by the name of IMPDH, inosine monophosphate dehydrogenase. It is this enzyme which is playing a crucial role in the production of the GTP(  guanosine triphosphate. So, by arresting the production of the GTP they have taken place that structure of the formation of genetic material, consequently resulting in apoptosis as well as cell death.

How to take Mycophenolate sodium 180mg?

The Mycophenolate sodium is taken according to the doctor’s directions. The medication is required to be consumed orally according to the doctor’s prescription. You can take it twice a day without a meal. This is required to be taken 1-2 hours after you have taken your food. Avoid inhalation of the dust, or coming in direct contact with the medicine with your skin or eyes. If accidentally it has occurred, immediately wash the area of your skin/eyes by using plain water.

Dosage of GLEOCEPT S -180

The indicated dosages differ according to the condition of the patient. Follow all the directions which are mentioned on the product label. Do not decrease/ increase or alter the dosage unless the doctor asked you to do the same.

Side effects of taking Mycophenolate sodium 180mg

Immediately talk to the physician in case you are having the symptoms of infection, flu-like signs, stain while urinating, alteration in vision, soreness/ wounds on the skin, or anything which is feeling painful/ warm

Some of the common undesirable impacts of taking GLEOCEPT S -180 include:

• Constipation
• Headache
• Diarrhea
• Nausea
• Vomiting
• Stomach upsetting
• Insomnia
• Gas bloating
• Gain in weight
• Pain in muscles/ joints
• Dizziness
• Anxiety
• Swollen hands/feet

Drug interactions

Certain medications may affect how Mycophenolate sodium is working. So always be cautious and tell the doctor if you are taking the below-mentioned drugs.

• activated charcoal
• acyclovir
• azathioprine
• cholestyramine
• cyclosporine
• ganciclovir
• metronidazole
• norfloxacin
• rifampin
• sevelamer
• valacyclovir,
• valganciclovir
• Birth control medications

This list does not include all the drugs that you should avoid while getting treated with GLEOCEPT S -180. So inform the doctor about all the medicines, whether it is prescription, over-the-counter or any herbal products you are taking

Warning & Precautions

• Before you start your course of treatment with GLEOCEPT S -180, inform your physician about the medical condition you are having, allergic reactivity, or in case you are a pregnant or lactating women
• People who are consuming Mycophenolate sodium shouldn’t not donate blood during their therapeutic procedure, and even 6 months after the last dosage is taken
• The medication may make the patient drowsy. This impairs the capability to drive or even work on heavy machinery. So don’t perform any risky tasks, unless and until you determine how this medication is impacting you
• People who are having hepatitis B & C infection may find it returning. So inform the doctor in case you have a medical history of such infections, and discuss with the doctor how this drug can affect your condition
• Communicate physician if you are having Lesch-Nyhan/ Keeley-Seegmiller disease. This is a hereditary disorder, that can affect the patient’s stomach/ digestive system or if you are having carcinoma, PKU(Phenyl Ketone Urea)/liver or kidney syndrome
• Do not take any shots or use a nasal spray, without the permission of the doctor
• Communicate physician in case you are experiencing losses in vision, lack of coordination, loss in memory or there are any symptoms of PML( Progressive Multifocal Leukoencephalopathy).

Storage conditions

• Make sure to store the Mycophenolate sodium 180mg at the condition of room temperature. The storage has to be done in a cool & dry environment, away from the falling of direct sunlight.

FAQs( Frequently Asked Questions)

• What is the frequency of taking the Mycophenolate sodium?

The frequency of the dosage is to be taken as per the doctor’s prescription and recommendations

• Is taking Mycophenolate sodium makes be addicted to it?

No, GLEOCEPT S -180 is not at all habit-forming. There are no cases of habit formation due to the intake of this Mycophenolate sodium have been reported!