Composition Imatinib mesylate (400mg)
Indication Chronic myelogenous leukemia, Dermatofibrosarcoma protuberans (DFSP), Gastrointestinal stromal tumors
Packaging 3x10 Tablets
SKU: GHAC-10 Categories: , Tags: ,

IMATISURE 400 is FDA-approved remedy for treating certain types of blood, stomach, and digestive tract cancers

Every year there is a significant rise in leukemia cases, with a greater need for specialized medical care, infrastructure as well as human resources for the treatment. The DFSP( dermatofibrosarcoma protuberans) is a relatively rare carcinoma leading to a tumor within the skin’s deeper layers. The growth of the tumor is initiated with the smaller and form skin patch and then it gets transformed into the raised nodule.

There are other types of carcinoma Gastrointestinal stromal tumors taking place in the Gastrointestinal system(majorly it occurs in the stomach/ small intestine). The IMATISURE 400 tyrosine kinase-inhibiting substance has been approved for the treatment of the above-mentioned cancers. The medication demonstrated its efficacy in curing the cancers of blood cells, intestine, skin cell carcinoma, bone marrow as well as stomach.


The IMATISURE 400 is composed of the chief compound Imatinib mesylate belongs to the category of kinase inhibitor which is arresting the signaling of proteins leading into the proliferation of the cancer cells. This is done for the curing of patients with Chronic myelogenous leukemia, acute lymphoblastic leukemia gastrointestinal stromal tumors(GIST) that are not been able to remove through surgical intervention, spread to other body parts or reappear even after the operation. So, this medication is administered for treating tumors existing in the stomach as well as the digestive tract

Composition of IMATISURE 400

The main active molecule existing in this anti-cancer drug is imatinib mesylate. This tyrosine kinase substance has got its approval from the FDA for the cure of the different forms of cancer. As it is a representation of the targeted therapy, it is activating certain specified downstream pathways.

Uses of IMATISURE 400

The IMATISURE 400 is indicated to be administered to patients with certain specific forms of cancers including:

  • Chronic myeloid leukemia
  • Acute lymphocytic leukemia
  • Gastrointestinal Stromal Tumor(GIST)

How IMATISURE 400 is acting?

This drug is demonstrating its action by arresting the cancer cells’ growth and carrying out the prevention of its spread from one tissue to the other in a distinctive part of the body. This medication is conducting the inhibition of proliferation as well as induces apoptosis within bcr-abl positive cancerous cells.

Side effects of IMATISURE 400

Some of the side effects of intake of this drug include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Taste changes
  • Mouth soreness
  • Appetite loss
  • Weightlessness
  • Indigestibility
  • Dryness
  • Burning sensation in heart
  • Pain in bone and muscles
  • Tingling sensation in skin
  • Insomnia
  • Sweating
  • Teary eyes

What to do?

  • If I forget the dosage

You have to take the missed medication whenever you recall. When the time of the next dosage is less than 12 hours then just stick to your regular schedule.

  • In case of overdosing emergency

If accidentally the patient has overdosed on IMATISURE 400, contact immediately the emergency room of the healthcare facility

How IMATISURE is administered?

The Imatinib mesylate is in tablet form taken through the mouth as per the recommendations of the physician. Generally, it is administered once or twice during the whole day. The anti-cancerous pill is required to be taken with a full glass of water after consumption of your food. The concentration of the medicine that the patient gets is dependent upon the factors which include general health, bodily issues as well as the condition which is likely to be treated. The physician will be determining dosage as well as the schedule.

What special precautionary measures need to be followed?

First of all communicate doctor if you are allergic to IMATISURE 400 or any other medications about the prescription, non-prescription, supplements, or vitamins that you are consuming or planning to take

  • Make sure to talk to the doctor about the herbal remediation you are taking for example; St. John’s Wort
  • Inform your physician if you have cardiac, lung, renal, or kidney disease
  • Also, communicate if you have a pregnancy or planning for that. It is important to rely on the birth control method while taking this medication and even after 2 weeks of the final process
  • Make sure to tell your doctor in case you are breastfeeding mother
  • Also if you have recently undergone surgery which includes dental, tell your doctor
  • The IMATISURE 400 tends to induce dizziness, drowsiness, or induces blurring of vision. So make sure not to drive or operate any machinery

Storage conditions

You can store the drug packet in a room that is dark and non-humid. Never store that medicine bottle in the bathroom. Make sure not to carry out the flushing of the drugs within the toilet or pour the same into the drain, unless and until you are instructed for doing so.

What drug & dietary instructions I need to undertake?

Certain specified drugs demonstrate interfering action with Imatinib mesylate. This also includes paracetamol. Some of the drugs are counter interacting with IMATISURE 400:

  • cyclosporin
  • dexamethasone
  • warfarin
  • antiviral medicines which treat AIDS
  • medicines treating bacterial infections
  • High cholesterol
  • high blood pressure
  • heart problems
  • mental disorders
  • depression

Dietary instructions

Make sure not to take grapefruit juice or wine while consuming the drug

Frequently Asked Questions(FAQs)

  • What happens if I stop taking IMATISURE 400?

This medication can be taken for several years. It is decided by the doctor and only the healthcare provider will tell you when you are required to stop its intake. Many people continue to consume this drug till the point its undesirable effects get too severe or the situation worsens.

  • Can I drive after taking IMATISURE 400?

This medication is known to induce drowsiness as well as dizziness for even light headiness in some of the patients. The patient must know the manner of how to react before starting driving or working on machinery.