Palsure 200

What is Palsure 200?

Palsure 200 is a prescription medication that contains Posaconazole 200 mg, an antifungal agent used to treat or prevent severe fungal infections. Posaconazole belongs to the triazole class of antifungals, effective against a broad spectrum of fungal pathogens.

What are the Uses of Palsure 200?

Palsure 200 is used for:

• Treatment of invasive Aspergillosis

• Treatment of oropharyngeal candidiasis (OPC)

• Prophylaxis of fungal infections in immunocompromised individuals (e.g., chemotherapy, bone marrow transplant recipients)

• Treatment of mucormycosis, especially when other antifungals are not effective

What are the Benefits of Palsure 200?

• Broad-spectrum antifungal coverage against Aspergillus, Candida, and other molds

• Useful in patients resistant to other antifungal drugs

• Effective in both treatment and prevention of fungal infections

• Well tolerated in long-term use for prophylaxis

How Does Palsure 200 Work?

Palsure 200 (Posaconazole) inhibits the enzyme lanosterol 14-alpha-demethylase, which is essential for the synthesis of ergosterol, a key component of fungal cell membranes. Disruption of ergosterol synthesis results in fungal cell death.

How to Take Palsure 200?

• Take as prescribed by your physician

• Preferably taken with food (high-fat meal enhances absorption)

• Swallow the tablet whole with water

• Do not crush or chew the tablets

Dosage of Palsure 200

General guidance (may vary per case):

• For prophylaxis: 300 mg twice on Day 1, then 300 mg once daily

• For treatment of OPC: 100 mg once daily after initial loading

• For invasive infections: As per specialist’s recommendation

Note: Always follow your doctor’s specific dosage instructions.

Missed Dose and Overdose

• Missed dose: Take it as soon as you remember. If it’s near the time for your next dose, skip the missed dose—do not double up.

• Overdose: Seek immediate medical attention. Symptoms may include nausea, vomiting, or liver toxicity.

What are the Available Strengths of Palsure?

• Palsure 200 mg tablets

• Other strengths may not be available under the same brand but are offered under generic Posaconazole in:

  • Oral suspension

  • Delayed-release tablets

  • Intravenous form (for hospital use)

Side Effects of Palsure 200

Common:

• Nausea

• Vomiting

• Diarrhea

• Headache

• Fever

Serious:

• Liver enzyme elevation

• QT prolongation (heart rhythm problem)

• Electrolyte disturbances (hypokalemia, hypomagnesemia)

• Allergic reactions

Interactions of Palsure 200

Avoid or monitor closely with:

• Rifampin

• Phenytoin

• Cyclosporine

• Statins

• Midazolam

• Proton pump inhibitors (may reduce absorption)

Always inform your doctor of all medications and supplements you’re taking.

Precautions of Palsure 200

• Monitor liver function tests regularly

• Avoid in patients with known hypersensitivity to Posaconazole

• Use with caution in patients with:

  • Liver or kidney disease

  • Heart rhythm disorders

• Pregnant or breastfeeding women should use only if clearly needed

Storage Information

• Store at room temperature (15–30°C / 59–86°F)

• Protect from moisture and heat

• Keep out of reach of children

Availability in the US and Australia

• US: Posaconazole is available under brand names like Noxafil. Palsure 200 may not be available by this brand name but can be substituted with a generic.

• Australia: Posaconazole is available, usually through prescription from a specialist or hospital; check for local brands.

Frequently Asked Questions (FAQ)

Q1. Is Palsure 200 safe for long-term use?

Yes, under medical supervision, especially for prophylaxis in high-risk individuals.

Q2. Can I take Palsure 200 with other antifungals?

Generally not recommended unless advised by a specialist.

Q3. How soon will I see improvement?

Relief may begin in a few days, but full course completion is essential.

Q4. Can I drink alcohol while on Palsure 200?

Avoid alcohol as it may increase the risk of liver toxicity.

Q5. What if I vomit after taking Palsure 200?

If vomiting occurs within 1 hour, you may need to take another dose. Consult your doctor.

Insight from Gleason Healthcare Medical Experts

Founded in 2012, Gleason Health Care has rapidly emerged as one of India’s leading pharmaceutical companies, specializing in the manufacturing and marketing of generic medications, hormonal therapies, nutraceuticals, and related healthcare products. Quality, innovation, and customer-centric service form the cornerstone of Gleason Health Care’s operational philosophy. The company embraces a technology-driven approach to meet the evolving demands of emerging markets and to drive sustainable growth.