Pazosure 200

What is Pazosure 200?

Pazosure 200 is a targeted anti-cancer medicine that contains Pazopanib, a tyrosine kinase inhibitor (TKI). It works by blocking specific enzymes (receptors) involved in cancer cell growth and the formation of blood vessels that feed tumors. It is typically used in treating advanced renal cell carcinoma (RCC) and soft tissue sarcoma (STS).

🎯 What are the Uses of Pazosure 200?

Pazosure 200 is prescribed for:

• Advanced Renal Cell Carcinoma (RCC) – kidney cancer that has spread or cannot be surgically removed.

• Advanced Soft Tissue Sarcoma (STS) – for patients who have previously received chemotherapy.

🌟 What are the Benefits of Pazosure 200?

• Slows tumor growth and spread

• Blocks blood vessel formation in tumors (anti-angiogenic)

• Improves progression-free survival in certain cancer types

• Convenient oral formulation (no hospital visit for infusions)

• Well-studied alternative to chemotherapy with a targeted approach

⚙️ How Does Pazosure 200 Work?

Pazosure 200 (Pazopanib) inhibits several tyrosine kinases including:

• VEGFR (Vascular Endothelial Growth Factor Receptors)

• PDGFR (Platelet-Derived Growth Factor Receptors)

• c-Kit

These enzymes are essential for cancer cell growth, spread, and angiogenesis. By blocking them, Pazosure starves tumors and slows cancer progression.

💊 How to Take Pazosure 200?

• Take once daily, on an empty stomach (1 hour before or 2 hours after food).

• Swallow the tablet whole with water—do not crush or chew.

• Try to take it at the same time each day.

🧪 Dosage of Pazosure 200

• Typical adult dose: 800 mg once daily.

• Pazosure 200 may be used in dose adjustment regimens (e.g., 200 mg or 400 mg based on tolerability).

• Doses may be reduced in patients with liver impairment or severe side effects.

Always follow your oncologist’s dosing instructions.

🕘 Missed Dose and Overdose

• Missed dose: Skip if close to the next dose. Do not double dose.

• Overdose: May cause severe liver toxicity, high blood pressure, or heart issues. Seek immediate medical help.

💊 What are the Available Strengths of Pazosure?

• Pazosure 200 mg tablet

• Pazosure 400 mg tablet

These allow flexible dosing as prescribed by your oncologist.

⚠️ Side Effects of Pazosure 200

Common Side Effects:

• Diarrhea

• Nausea, vomiting

• Fatigue

• Loss of appetite

• Change in hair color

• High blood pressure

Serious Side Effects:

• Liver toxicity (elevated liver enzymes)

• Heart rhythm problems (QT prolongation)

• Bleeding or clotting issues

• Kidney function changes

• Delayed wound healing

🔄 Interactions of Pazosure 200

May interact with:

• CYP3A4 inhibitors/inducers (e.g., ketoconazole, rifampicin)

• Antacids and PPIs (may affect absorption)

• Blood thinners (e.g., warfarin)

• Grapefruit juice (can increase toxicity risk)

Always tell your doctor about all medications and supplements you’re using.

⚠️ Precautions of Pazosure 200

• Monitor liver function regularly.

• Check blood pressure frequently.

• Not recommended during pregnancy or breastfeeding.

• Caution in patients with:

  • Heart problems

  • Liver disorders

  • History of bleeding

  • Upcoming surgery (discontinue at least 7 days before)

🧊 Storage Information

• Store at room temperature (15°C – 30°C).

• Keep in original packaging away from moisture and heat.

• Keep out of reach of children and pets.

🌍 Availability in the US and Australia

• United States:

  • Pazopanib is available as Votrient® (by Novartis).

  • Pazosure brand may not be FDA-approved; could be available through international pharmacies or special import.

• Australia:

  • Pazopanib is available via PBS under Votrient®.

  • Pazosure brand may be accessed through special access schemes or import channels.

❓ Frequently Asked Questions (FAQs)

1. Is Pazosure 200 a chemotherapy drug?

No. It’s a targeted therapy that blocks specific enzymes in cancer cells.

2. Can I take it with food?

No. Take it on an empty stomach for proper absorption.

3. How long should I take it?

As long as prescribed. Your oncologist will monitor your response and adjust duration.

4. Can it cause liver damage?

Yes, regular liver function monitoring is essential.

5. Can I drive or work while taking Pazosure?

If you feel fatigued or dizzy, avoid driving or operating machinery.

Insight from Gleason Healthcare Medical Experts

Founded in 2012, Gleason Health Care has rapidly emerged as one of India’s leading pharmaceutical companies, specializing in the manufacturing and marketing of generic medications, hormonal therapies, nutraceuticals, and related healthcare products. Quality, innovation, and customer-centric service form the cornerstone of Gleason Health Care’s operational philosophy. The company embraces a technology-driven approach to meet the evolving demands of emerging markets and to drive sustainable growth.